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女贞子中一个新的裂环环烯醚萜苷类成分
引用本文:张廷芳,段营辉,屠凤娟,戴毅,姚新生.女贞子中一个新的裂环环烯醚萜苷类成分[J].中草药,2012,43(1):20-22.
作者姓名:张廷芳  段营辉  屠凤娟  戴毅  姚新生
作者单位:1. 暨南大学中药及天然药物研究所,广东广州,510632
2. 暨南大学中药及天然药物研究所,广东广州510632;广东省中药药效物质基础及创新药物研究重点实验室,广东广州510632
3. 沈阳药科大学,辽宁沈阳,110016
4. 暨南大学中药及天然药物研究所,广东广州510632;沈阳药科大学,辽宁沈阳 110016
基金项目:深圳市基础研究计划(JC200903170506A)
摘    要:目的研究女贞子的化学成分。方法采用硅胶、ODS、Sephadex LH-20和RP-HPLC等色谱分离手段对女贞子70%乙醇提取物的醋酸乙酯萃取部位进行分离纯化,并根据理化性质和波谱数据鉴定化合物的结构。结果分离得到1个裂环环烯醚萜苷类化合物,鉴定为6′-O-肉桂酰基-8-表-金吉苷酸(6′-O-cinnamoyl-8-epi-kingisidic acid,1)。结论化合物1为新化合物。

关 键 词:女贞子  女贞  醋酸乙酯部位  裂环环烯醚萜苷  6′-O-肉桂酰基-8-表-金吉苷酸
收稿时间:2011/9/21 0:00:00

A new secoiridoid glucoside in fruits of Ligustrum lucidum
ZHANG Ting-fang,DUAN Ying-hui,TU Feng-juan,DAI Yi and YAO Xin-sheng.A new secoiridoid glucoside in fruits of Ligustrum lucidum[J].Chinese Traditional and Herbal Drugs,2012,43(1):20-22.
Authors:ZHANG Ting-fang  DUAN Ying-hui  TU Feng-juan  DAI Yi and YAO Xin-sheng
Institution:1,3 1.Institute of Traditional Chinese Medicine and Natural Products,Jinan University,Guangzhou 510632,China 2.Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,Guangzhou 510632,China 3.Shenyang Pharmaceutical University,Shenyang 110016,China
Abstract:Objective To study the chemical constituents from the fruits of Ligustrum lucidum.Methods The chemical constituents in ethyl acetate fraction of 70% ethanol extract from the fruits of L.lucidum were isolated and purified by column chromatography over silica gel,ODS,Sephadex LH-20,and HPLC.The structures were identified on the basis of physicochemical properties and spectral data analyses.Results A compound,secoiridoid glucoside,was isolated and identified as 6′-O-cinnamoyl-8-epi-kingisidic acid(1).Conclusion Compound 1 is a new one.
Keywords:fruits of Ligustrum lucidum Ait    Ligustrum lucidum Ait    ethyl acetate fraction  secoiridoid glucoside  6′-O-cinnamoyl8-epi-kingisidic acid
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