参松养心胶囊水提液陶瓷膜除杂工艺研究

目的考察不同规格陶瓷膜对中药大品种参松养心胶囊水提液除杂的效果,并优化工艺参数。方法以参松养心胶囊水提液为研究对象,比较3种不同孔径的陶瓷膜在不同条件下,对膜通量衰减、药液有效成分保留率等方面的影响。结果滤过孔径为100 nm的陶瓷膜对参松养心胶囊水提液滤过效果较好,膜通量及芍药苷转移率均较高,最佳滤过条件为进液压力0.15～0.22 MPa,滤过温度20℃。结论陶瓷膜滤过技术可较好地对参松养心胶囊水提液进行除杂,该技术可进一步推广到其他中药水提液的除杂工艺中。

Application of ceramic filter membrane in purification technology of water extract from Shensong Yangxin Capsule

Objective To observe the effect of different pore diameter membranes on technologies of water extract from Shensong Yangxin Capsule and optimize the parameters.Methods Three different membranes were tested to observe the changes in membrane flux and the retention of effective components.Results The membrane with 100 nm diameter had the greater membrane flux,the transfer rates of paeoniflorin was the highest.The optimum conditions were that the operation differential pressure was 0.15—0.22 MPa,the operation temperature was 20 ℃.Conclusion A good result can be obtained by adopting the technology of ceramic membranes filtration to purify Shensong Yangxin Capsule,which provides the foundation for the application of ceramic membranes micro-filtration in the purification of water extract of other Chinese materia medica.