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颠胃酸口服液的消化活力测定
引用本文:常明泉,陈芳,朱建成,吕明. 颠胃酸口服液的消化活力测定[J]. 中国药事, 2012, 26(8): 888-890
作者姓名:常明泉  陈芳  朱建成  吕明
作者单位:湖北医药学院附属太和医院,十堰,442000
摘    要:目的 建立颠胃酸口服液消化活力测定方法.方法 用酪氨酸为对照品,牛血红蛋白为底物,水浴温度37℃±0.5℃,紫外分光光度法,测定波长275 nm.结果 颠胃酸口服液平均消化活力为33.8μ·mL-1,高于标示量(24μ·mL-1),回收率为98.2%,RSD为0.96%(n=6).结论 该方法用于颠胃酸口服液的消化活力测定,操作便利,试验条件稳定,结果重复性好.

关 键 词:颠胃酸口服液  消化活力  分光光度法  胃蛋白酶

Digestive Activity Assay in Dianweisuan Oral Liquid
Chang Mingquan , Chen Fang , Zhu Jiancheng , Lv Ming. Digestive Activity Assay in Dianweisuan Oral Liquid[J]. Chinese Pharmaceutical Affairs, 2012, 26(8): 888-890
Authors:Chang Mingquan    Chen Fang    Zhu Jiancheng    Lv Ming
Affiliation:(Taihe Hospital Affiliated to Hubei Medical College, Shiyan 442000)
Abstract:Objective To establish a method for the determination of digestive activity in Dianweisuan Oral Liquid. Methods The digestive activity was determined by UV spectrophotometry at 275 nm. Tyrosine was selected as the reference substance, bovine hemoglobin was chose as the substrate, and the water bath temperature was 37 ℃ -0.5 ℃. Results The digestive activity of Dianweisuan Oral Liquid was 33.8 μ·mL-1 , which is higher than the labeled amount (24μ·mL-1). The recovery was 98.2%, RSD 0.96% (n = 6). Conclusion The method is convenient, reproducible, and can be used for the digestive activity determination of Dianweisuan Oral Liquid.
Keywords:Dianweisuan Oral Liquid  digestive activity  UV spectrophotometry  pepsin
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