早期瑞舒伐他汀干预对不稳定型心绞痛支架术后血清妊娠相关蛋白A和高敏C反应蛋白的影响 |
| |
引用本文: | 翁建新,刘强,左辉华,王丽丽,张敏州,魏熠,陈绮映.早期瑞舒伐他汀干预对不稳定型心绞痛支架术后血清妊娠相关蛋白A和高敏C反应蛋白的影响[J].中医药研究,2011(7):781-783. |
| |
作者姓名: | 翁建新 刘强 左辉华 王丽丽 张敏州 魏熠 陈绮映 |
| |
作者单位: | [1]广东省深圳市孙逸仙心血管医院、深圳市心血管病研究所,518102 [2]广东省中医院,518102 |
| |
摘 要: | 目的探讨瑞舒伐他汀对血脂水平正常的不稳定型心绞痛患者行PCI术后妊娠相关蛋白A(PAPP-A)及高敏C反应蛋白(hs-CRP)的影响。方法 56例血脂水平正常的不稳定型心绞痛患者,随机分为瑞舒伐他汀组和常规治疗组,两组患者分别于PCI术前、术后24 h、术后1个月检测血清PAPP-A和hs-CRP水平。结果两组患者术后24 h与术前比较,血清PAPP-A和hs-CRP浓度均有明显升高,但两组间比较,无明显差异;术后1个月,两组血清PAPP-A和hs-CRP水平与术后24 h比较,均有回降,但瑞舒伐他汀组较常规治疗组回降更为明显,两者存在统计学意义(P〈0.05)。结论早期使用瑞舒伐他汀能更有效降低不稳定型心绞痛患者PCI术后PAPP-A和hs-CRP水平。
|
关 键 词: | 瑞舒伐他汀 不稳定型心绞痛 妊娠相关蛋白A 高敏C反应蛋白 经皮冠脉介入治疗 |
Influence of Rosuvastatain on Plasma PAPP-A and hs-CRP after PCI in Unstable Angina Pectoris |
| |
Institution: | Weng Jianxin,Liu Qiang,Zou Huihua,et al Sun Yatsen Cardiovascular Hospital,Shenzhen(Shenzhen 518102) |
| |
Abstract: | Objective To investigate the effects of rosuvastatain on the pregnancy-associated plasma protein-A(PAPP-A) and high sensitivity C-reactive protein(hs-CRP) after percutaneous coronary intervention(PCI) in patients(pts) with unstable angina pectoris(UAP).Methods Fifty-six pts with UAP were randomly divided into two groups:Rosuvastatain group(n=30) treated with rosuvastatain and control group(n=26) treated with routine treatment.The levels of PAPP-A and hs-CRP were detected before PCI and at 24 hours,1 month after PCI.Results The levels of PAPP-A and hs-CRP were increased at the 24 hours after PCI in two groups(P0.05).The levels of PAPP-A and hs-CRP were decreased at 1 month after PCI in two groups(P0.05).The levels of PAPP-A and hs-CRP were obviously lower than that in control group(P0.05).Conclusion Rosuvastatain could decrease the level of PAPP-A and hs-CRP significantly in pts with UAP after PCI. |
| |
Keywords: | Rosuvastatain unstable angina pectoris pregnancy-associated plasma protein-A high sensitivity C-reactive protein percutaneous coronary intervention |
本文献已被 维普 等数据库收录! |
|