| 高血压大鼠某些周缘神经节中氧化一氮合酶的分布 |
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| 引用本文： | 于恩华,沈丽,杨嘉,许鹿希.高血压大鼠某些周缘神经节中氧化一氮合酶的分布[J].解剖学报,1994(2). |
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| 作者姓名： | 于恩华 沈丽 杨嘉 许鹿希 |
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| 作者单位： | 北京医科大学解剖学教研室 |
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| 摘 要： | 高血压大鼠某些周缘神经节中氧化－氮合酶的分布（北京医科大学解剖学教研室，北京１０００８３，于恩华，沈丽，杨嘉，许鹿希）氧化－氮（ｎｉｔｒｉｃｏｘｉｄｅ，ＮＯ）作为一种特殊的神经活性物质已经为人们接受，氧化－氮合酶（ｎｉｔｒｉｃｏｘｉｄｅｓｙｎｔｈａｓ...
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AN ELECTRON MICROSCOPIC STUDY OF MULTIPLE INNERVATIONS OF NEURONS IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS |
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| Zhu Chang-geng,Zhang Xi-jing,Liu Qing-ying,Cai Qiu-yun,Wei Ying.AN ELECTRON MICROSCOPIC STUDY OF MULTIPLE INNERVATIONS OF NEURONS IN THE HYPOTHALAMIC PARAVENTRICULAR NUCLEUS[J].Acta Anatomica Sinica,1994(2). |
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| Authors: | Zhu Chang-geng Zhang Xi-jing Liu Qing-ying Cai Qiu-yun Wei Ying |
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| Abstract: | In order to further explore the synaptic regulatory mechanism of the hypothalamic neuroendocrine,the multiple innervations of neurons in the hypothalamic paraventricular nucleus(PVN)of rats have been studied by combined method of electron microscopic cytochemistry with double immunoelectron microscopy.First,the CA nerve terminals were lesiond by 6-OHDA,then the peptidergic(OT or SP)and GABAergic neurons were double labeled by pre embedding immunoelectron microscopy using DAB and TMB as chromogens.The results showed that there were peptide(OT,SP)and amino acid(GABA)-like neurons and CA nerve terminals in the PVN,OT neurons received GABA and CA innervations through axo-dendritic synapses,SP neurons received CA and SP innervations through axo-dendritic synapses and the GABA neurons might receive OT,SP,CA and GABA innervations through axo-dendritic synapses.The present study provided the ultrastructural evidences for the multiple innervations of the hypothalamic neurons for the first time.Its significance lies in providing the morphological basis for simultaneously investigating the multiple synaptic regulations of the hypothalamic neuroendocrine. |
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| Keywords: | Hypothalamus Paraventricular nucleus Neuroendocrine Synaptic regulation Immunoelectron microscopy |
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