广东地区肺鳞癌和肺腺癌危险因素对比分析

运用ＡＳＲＳ单因素、多因素分析方法，对广东地区１６９例肺鳞癌和１３５例肺腺癌进行了１：１配比病例对照研究。比较分析显示：主动吸烟与肺鳞癌的联系更为密切。被动吸烟在肺腺癌中则可能有相对较高的病因地位。多变量分析表明粉尘类职业、印染化工类职业、肺结核、慢支以及吸烟指数（≥１９，≥３７）为广东地区重要的危险因素，综合人群归因危险度为８２．２１％；肺腺癌的重要危险因素则是家庭被动吸烟年数、吸烟指数（≥２６）、慢支，综合人群归因危险度为６８．９２％。为广东地区肺鳞癌和肺腺癌的病因防治提出了重点。

Comparative Analysis of Risk Factors Between Lung Squamous Cell Carcinoma and Adenocarcinoma in Guangdong Territory

The single and multiple factor ASRS(Analytical system of risk for states)was applied in an 1: 1 case-control study to comparatively analyze the cases of lung squmous cell carcinoma (169 cases) and adenocarcionma (135 cases ) from Guangdong territory. The results showed that the association between active smoking and lung squmous cell carcinoma was much closer than that of adenocarcinoma. And passive smoking may play an relatively important pathogenic role in adenocarcinoma. According to multiple analysis, dust work-type occupation, dyeing chemical work-type cccupation, tuberculosis,chronic bronchitis and active smoking index(>=19, >=37)were much important risk factors of squmous cell carcinoma in Guangdong, the summary AR was 82. 2%. The important risk factors of adenocarcinoma was family passive smoking (year), smoking index (>=26), and chronic bronchitis, summary AR of which was 68. 92%. So this paper provided anlocal point in prevention of lung cancer in Guangdong territory.