郑州市小儿呼吸道病毒性感染病原学初析

目的探讨本市小儿呼吸道病毒性感染的病原学分布现状,为防治工作提供资料。方法应用ELISA法检测患儿急性期血清中7种病毒(IV、PIV、RSV、ADV、CBV、EBV、MP)特异性IgM抗体,以了解病原学分布。结果从8 594例被检患儿血清中,检出相关IgM抗体阳性2 907例,总阳性率为34.0%。含单一病毒感染占85.6%,2种混合感染占14.4%。单一病毒感染中IV占首位(29.4%),其余依次为MP(21.0%)、ADV(14.3%)、RSV(13.1%)、PIV(12.9%)、EBV(4.7%)、CBV(4.6%)。结论IV、MP、ADV、RSV、PIV为本地致小儿呼吸道感染的主要流行病原体。3岁前(新生儿除外)因免疫力低,对各种病毒的易感率高,故需关注此年龄段的预防工作。对疑似病例作IgM检测,能及时提供病原学诊断依据,并可作为流行病学调查的信息资料。

Analysis of the pathogeny of virus infection in children's respiratory track

Objective To explore the distribution condition of virus infection in children's respiratory track this city,to provide evidence for prevention.Methods to detect the special IgM antibody of 7 kinds of virus(IV,PIV,RSV,ADV,CBV,EBV,MP) by using ELISA.Results the serum antibody IgM of 2907 from 8549 children were positive.The total positive rate was 34%,among them signal virus infection 85.6%,2 kinds of virus infection 14.4%.IV is the first cause of single infection(29.4%),in turn MP(21%),ADV(14.3%),RSV(13.1%),PIV(12.9%),EBV(4.7%),CBV(4.6%).Conclusions IV,MP,ADV,RSV,PIV are the primary prevalent pathogeny of children's respiratory infection this area.Children below 3 years old exception neonate are easy to be infected,so they should be paid more attention for prevention.The suspect cases should be detected IgM to provide the diagnosis evidence.