| 艾迪联合长春瑞滨加顺铂方案治疗晚期非小细胞肺癌疗效观察 |
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| 引用本文： | 范强,谢其根,王震吾,杭晓声. 艾迪联合长春瑞滨加顺铂方案治疗晚期非小细胞肺癌疗效观察[J]. 中国现代医药杂志, 2008, 10(8) |
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| 作者姓名： | 范强 谢其根 王震吾 杭晓声 |
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| 作者单位： | 江苏省无锡市第四人民医院,214062 |
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| 摘 要： | 目的观察和评价艾迪注射液联合长春瑞滨加顺铂方案（NP方案）治疗晚期非小细胞肺癌的疗效和毒性。方法将我科近几年收治的52例晚期非小细胞肺癌患者随机分为联合治疗组和化疗组：联合治疗组采用艾迪注射液联合长春瑞滨加顺铂方案，化疗组采用长春瑞滨加顺铂方案（NP方案）。3周期化疗后进行疗效，毒性对比研究。结果联合治疗组和化疗组近期有效率分别为46％和42％，疾病进展时间（TTP）分别为6．8月和5.3月．中位生存时间分别为10．7月和9．4月，1年生存率分别为42％和38％。两组间比较差异均无显著性（P〉0．05）。联合治疗组在恶心、呕吐、骨髓抑制等毒性反应发生率方面低于化疗组，差异有显著性（P〈0．05）。结论艾迪注射液联合长春瑞滨加顺铂方案与NP方案相比．疗效相似，但毒性反应低于NP组，患者更易接受，可广泛用于临床。
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| 关 键 词： | 艾迪注射液 长春瑞滨 顺铂 肺肿瘤 化学疗法 |
Clinical study on efficacy of Aidi injection combined with vinorelbine and cisplatin in the treatment of advanced non-small cell lung cancer |
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| Fan Qiang,Xie Qigen,Wang Zhenwu,et al.. Clinical study on efficacy of Aidi injection combined with vinorelbine and cisplatin in the treatment of advanced non-small cell lung cancer[J]. Modern Medicine Journal of China, 2008, 10(8) |
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| Authors: | Fan Qiang Xie Qigen Wang Zhenwu et al. |
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| Affiliation: | Fan Qiang,Xie Qigen,Wang Zhenwu,et al.The 4th Hospital of Wuxi,Wuxi 214062 |
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| Abstract: | Objective To observe efficacy, toxicity and side effects ofAidi injection combined with vinorelbine and cisplatin in the treatment of advanced non-small cell lung cancer(NSCLC). Methods Fifty-two advanced NSCLC patients were randomized into two groups,26 cases were treated with Aidi injection combined with vinorelbine and cisplatin as the trial group, and 26 cases were treated with vinorelbine and cisplatin as the control group. The efficacy was estimated after 3 cycles. Results The response rate, time to p... |
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| Keywords: | Aidi injection Vinorelbine Cisplatin Lung neoplasms Chemotherapy |
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