| Abstract: | Phase changes of the functional activity of cells of the mononuclear phagocyte system are shown on a model of closed fracture of the femur in laboratory rodents. Analogous changes included the dynamics of both number and activity of the bone marrow hemopoietic islets. The parameters studied fall in the early post-traumatic stage and rise during the active phase of osteogenesis. It is concluded that there is an interrelationship between bone tissue and the hemopoietic and macrophage systems during osteogenesis, which is, in particular, realized via changes in hemopoietic islet formation. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, No 4, pp. 433–434, April, 1995 Presented by E. D. Gol'dberg, Member of the Russian Academy of Medical Sciences |
