儿童股骨头缺血性坏死

儿童股骨头缺血性坏死又称Perthes病、儿童股骨头无菌性坏死，目前认为它是一种自限性疾病，但病因未明。所谓自限性或自愈性，是指股骨头的坏死最终可自然修复而痊愈。但其后遗的股骨头畸形，可导致髋关节负重和活动功能的障碍，甚至致残致畸。此病治疗的目的在于减轻临床症状，改善髋关节功能，预防病变的进行性加重，使股骨头能获得良好的包容，获得生物学塑型而恢复原有的形状。儿童股骨头缺血性坏死的治疗方法众多，但疗效均尚未令人满意;其中既有针对病因（尤其是改善缺血）而设计的治疗方案，又有针对病理演变规律，防止股骨头畸形而设计的治疗方案，使人难以选择。本文介绍了近年儿童股骨头缺血性坏死的研究进展。

Perthes disease

Legg-Calve-Perthes disease (LCPD), known as Perthes disease or aseptic necrosis of femoral head in children, is generally considered as a self-limited disease. Self-limiting or self-healing means  the necrotic femoral head can be finally recovered spontaneously, but the sequela of femoral head malformation could result in the dysfunction of hip joint’s weight bearing or moving, even lead to disabi-lities. The goals for treating LCPD are to alleviate clinical symptoms, improve the functions of hip joint, prevent the deterioration in the symptoms, make the femoral head a good inclusion to gain the biological plastic and restore the original shape. Although the approaches for LCPD treatment are many, such as targeting the etiology (particularly improve the ischemia) or targeting the pathological development to prevent femoral head deformity, none of them receive satisfactory results. This review summarized the recent progress in the study of LCPD.