首页 | 本学科首页   官方微博 | 高级检索  
     


Vitamin A in Skin and Hair: An Update
Authors:Christine A. VanBuren  Helen B. Everts
Affiliation:Department of Nutrition and Food Sciences, Texas Woman’s University, Denton, TX 76209, USA;
Abstract:Vitamin A is a fat-soluble micronutrient necessary for the growth of healthy skin and hair. However, both too little and too much vitamin A has deleterious effects. Retinoic acid and retinal are the main active metabolites of vitamin A. Retinoic acid dose-dependently regulates hair follicle stem cells, influencing the functioning of the hair cycle, wound healing, and melanocyte stem cells. Retinoic acid also influences melanocyte differentiation and proliferation in a dose-dependent and temporal manner. Levels of retinoids decline when exposed to ultraviolet irradiation in the skin. Retinal is necessary for the phototransduction cascade that initiates melanogenesis but the source of that retinal is currently unknown. This review discusses new research on retinoids and their effects on the skin and hair.
Keywords:vitamin A   hair follicle stem cells   melanocyte stem cells   melanocyte   retinoids
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号