| 高压氧疗对高海拔地区大鼠肺动脉压及血清血管紧张素转换酶的影响 |
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| 引用本文： | 吴意华,马清太.高压氧疗对高海拔地区大鼠肺动脉压及血清血管紧张素转换酶的影响[J].高原医学杂志,1995,5(3):12-14. |
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| 作者姓名： | 吴意华 马清太 |
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| 作者单位： | 青海省高原医学科学研究所氧舱科 |
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| 摘 要： | 本实验利用移居高原的Ｗｉｓｔａｒ大鼠在采用常规高压氧治疗一疗程后，用入导生理记录仪浊体、动脉压、取血浊血清血管紧张素转换酶活性，发现治疗后肺动脉平均后有非常显著下降（Ｐ〈０．０１）；血清轿管紧张素转换酶活性显著增强（Ｐ〈０．０５）；提示高原地区运用高太氧疗对肺动脉高压有一定治疗作用；从血清血管紧张素转换酶活性变化中未有证实高夺氧对肺组织的损伤。
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| 关 键 词： | 高压氧治疗 高原 血管紧张素 转换酶 肺动脉压 |
EFFECT OF HYPERBARIC OXYGEN ON PULMONARY ARTERY PRESSURE AND SERUM
ANGIORENSION CONVERTING ENZYME IN ALTITUDE RATS |
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| Wu Ymua,et al.EFFECT OF HYPERBARIC OXYGEN ON PULMONARY ARTERY PRESSURE AND SERUM
ANGIORENSION CONVERTING ENZYME IN ALTITUDE RATS[J].Journal of High Altitude Medicine,1995,5(3):12-14. |
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| Authors: | Wu Ymua |
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| Institution: | Qinghai High Altitude Medical Sciences Institute |
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| Abstract: | he direct
systemic and pulmonary artery pressrue and activity of serum
angiotension convertingenzyme(ACE)in Wistar rats migrated into high
altitude were separately measured before and after hy-perbatic
oxygen exposure( HOE.The results showed that the mean pulmonary
artery pressure dropped significantly(P<0. 01)and the activity of
serum ACE rose significantly (p< 0.05)afterHOE. It was indicated that
hyperbaric oxygen may show therapeutic effect on pulmonary
hypertensionin human. The lung tissues did not show impairment due to
active altering of ACE. |
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| Keywords: | Hyperbaric oxygen Pulmonary hyperteiision High altitude Angioteilsion converting enzyme |
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