| 吸入性损伤患者血浆IL-8水平的变化 |
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| 引用本文： | 郑健生,方向东,郑庆亦,陈锦河. 吸入性损伤患者血浆IL-8水平的变化[J]. 南方医科大学学报, 2000, 20(6): 551-552 |
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| 作者姓名： | 郑健生 方向东 郑庆亦 陈锦河 |
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| 作者单位： | 1. 解放军第175医院烧伤整形科，福建 漳州 363000
2. 第一军医大学分子免疫学研究所，广东 广州 510515 |
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| 摘 要： | 目的 探讨吸入性损伤患者血浆白细胞介素8（IL-8）水平变化与损伤时间、损伤程度之间的关系。方法 收集27例吸入性损伤患者血浆，采用ELISA方法，分别于伤后12 h及1、2、4、7 d测定血浆中IL-8水平。结果 吸入性损伤患者血浆IL-8水平于伤后１d内就明显升高，持续时间超过７d。结论 吸入性损伤能诱导机体产生IL-8，IL-8能影响全身免疫反应，并与吸入性损伤严重程度呈正相关。
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| 关 键 词： | 吸入性损伤 白细胞介素8 |
| 文章编号： | 1000-2588（2000）06-0551-02 |
| 修稿时间： | 2000-08-12 |
Changes of plasma IL-8 levels in patients with inhalation injury |
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| ZHENG JIAN-sheng,FANG Xiang-dong,ZHENG Qing-yi,CHEN Jin-he. Changes of plasma IL-8 levels in patients with inhalation injury[J]. Journal of Southern Medical University, 2000, 20(6): 551-552 |
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| Authors: | ZHENG JIAN-sheng FANG Xiang-dong ZHENG Qing-yi CHEN Jin-he |
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| Affiliation: | ZHENG Jian-sheng1,FANG Xiang-dong2,ZHENG Qing-yi1,CHEN Jin-he1 |
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| Abstract: | Objective To observe the changes of plasma IL-8 levels and their association with the severity of and the passage of time after inhalation injury. Methods The plasma was separated from blood samples of 27 patients 12 h, 1, 2, 4 and7 d after inhalation injury. The IL-8 level in the plasma was determined by ELISA. Result IL-8 levels were significantly increased on day 1 and kept a high level for a period over 7 d. Conclusion Inhalation injury can induce the production of IL-8, and IL-8 level is positively correlated with the by severity of inhalation injury. |
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| Keywords: | inhalation injury interleukin-8 |
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