广东省女性绝经后原发性骨质疏松症调查分析

目的探讨广东省女性绝经后骨密度的变化规律及其影响因素相关分析。方法本研究通过对广东省50～87岁的1772名中老年人完成骨质疏松症问卷调查和进行双能X-ray骨密度测量。筛选绝经后原发性骨质疏松症患者274例,以5岁为1个年龄段,将其分成7个组。分析腰椎和髋部BMD值的变化规律。体重指数、脂肪含量与骨密度的关系。结果广东省不同城市女性原发性骨质疏松症患病率为11.1%～19.2%,总体患病率为15.5%。体重指数与髋部neck、Total骨密度相关系数(r=0.282,r=0.272,P<0.05),脂肪含量与腰椎正位Total骨密度相关系数(r=0.086,P<0.05)。结论广东省女性骨质疏松症患者腰椎骨密度在55～65岁和70～79岁两个年龄段丢失明显,髋部骨密度丢失在65岁以后下降速率加快。体重指数与髋部骨密度值有一定相关性,脂肪含量和腰椎骨密度值有较小相关性。

Investigation and analysis of primary osteoporosis in postmenopausal women in Guangdong province

Objective To explore the change role of bone mineral density(BMD) and related factors in postmenopausal women in Guangdong province.Methods By investigating 1772 50～87 years old Guangdong inhabitants using questionnaire and BMD measurement with dual energy X-ray absorptiometry,274 postmenopausal osteoporosis cases were found.They were divided into 7 groups according to a 5-year-old division.The changes of BMD in the lumbar vertebrae(LV) and proximal femur(PF) and the correlation among body mass index(BMI),mass of fat,and BMD were analyzed.Results The prevalence of osteoporosis was 11.1～19.2% in various cities of Guangdong province,with 15.5% in the whole.The linear correlation coefficients between BMI and BMD of the femoral neck and total hip were 0.282 and 0.272(P<0.05).The linear correlation coefficient between mass of fat and BMD of the lumbar vertebrae was 0.086(P<0.05).Conclusion Bone mass loss of the lumbar vertebrae occurs obvious in women of 55～65 years old and 70～79 years old.Bone mass of the hip reduces quickly after the 65 years old.It is partially correlated between BMI and BMD of the hip.The correlation between mass of fat and BMD of the lumbar vertebrae is less.