瘢痕疙瘩切除后行浅表放疗的Logistic回归分析

目的:研究瘢痕疙瘩切除后行浅表放疗的最佳时机、研究影响其复发的因素。方法:分析105例瘢痕疙瘩切除后行浅表放疗的效果,分析性别、年龄、病变部位、瘢痕疙瘩面积、感染及放疗时机等与瘢痕疙瘩复发的关系。结果:术后2～6天,放疗有效率93.1%;术后7～10天,放疗有效率65.3%,差异有统计学意义;多因素Logi sti c回归分析筛选出影响瘢痕疙瘩复发的因素是放疗时机、瘢痕疙瘩面积;放疗时间OR=3.82(P0.05),病变面积哑变量1的OR=5.36(P0.05,)病变面积哑变量2的OR=8.69(P0.05)。结论:瘢痕疙瘩切除术后2～6天行浅表放疗是防止瘢痕增生及瘢痕疙瘩复发的有效方法;瘢痕疙瘩的复发可能与瘢痕疙瘩病变面积有关。

Logistic regression analysis of superficial radiotherapy after resection for keloid

Objective To investigate the optimal opportunity for superficial radiotherapy after resection of keloid,and investigate the influenceing factors of recurrence.Methods 105 cases with keloid removing operation were analysed by the superficial radiotherapy effects.Analysed the sex,age,the location of pathological changes,size of keloid,infection and radiotherapy opportunity with the relationship of keloid recurrence.Results After 2-6 days operation,the effective rates of radiotherapy was 93.1%;After 7～10 days operation,the effective rates was 65.3%,the differences had statistical significant;The multi-factor logistic regression analysis selected that the factor influencing the keloid recurrence was radiotherapy time and size of keloid.Radiotherapy time OR=3.82（P〈0.05）,Dummy variable 1 of pathological size OR=5.36（P〈0.05）,Dummy variable 2 of pathological size OR=8.69（P〉0.05）.Conclusion After keloid removing operation,the superficial radiotherapy performed on day 2 to day 6 was an effective way to prevent the recurrence of keloid.Recurrence of keloid was possible correlated with the keloid pathological size.