脑出血伴脑白质疏松症76例分析

目的探讨脑白质疏松症(LA)对脑出血的影响。方法回顾性分析脑出血伴LA患者头颅核磁共振影像特点,比较脑出血组和对照组LA发生率和严重程度的差异。结果脑出血组的LA发病率(80.26%)显著高于对照组(65.07%)(P=0.044);脑出血组LA严重程度(3.33±2.45)高于对照组(2.59±2.45)(P=0.028);脑出血伴LA者出血量大于非LA者(P=0.048);多因素Logistic回归分析示年龄、高血压及高脂血症与LA的发生率显著相关。结论LA与脑出血相互影响,脑出血为LA的危险因素,LA影响脑出血量。

Analysis of 76 cases of intracerebral hemorrhage with leukoareosis

Objective To investigate the effect of leukoareosis （LA） on intracerebral hemorrhage（ICH）. Methods The datum of characteristic of nuclear magnetic resonance of ICH patients with LA were analyzed retrospectively. Then the incidence of LA and the degree of severity were compared between ICH group and control group. Results The incidence of LA in ICH group （ 80.26% ） was obviously higher than that in control group （ 65.07 % ） （ P = 0. 044） ; The degree of severity of LA in ICH group （ 3.33 ± 2.45 ） was higher than that in control group （ 2.59 ± 2.45 ） （ P = 0. 028 ）. Compared to the patients of ICH without LA, the volume of hemorrhage in ICH patients with LA were more （ P = 0. 048 ） ; In the multivariate logistic regression analysis, age,hypertension and hyperlipemia were relate to increase the risk of LA. Conclusion ICH is the risk of LA. LA has a positive relativity with ICH,and it may increase the volume of hemorrhage.