| 文拉法辛对慢性精神分裂症的辅助治疗作用 |
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| 引用本文： | 刘昊,朱怀轩,赵勤,谭权.文拉法辛对慢性精神分裂症的辅助治疗作用[J].临床精神医学杂志,2009,19(4). |
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| 作者姓名： | 刘昊 朱怀轩 赵勤 谭权 |
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| 作者单位： | 重庆市精神病院,400038 |
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| 摘 要： | 目的:评价阿立哌唑合并文拉法辛缓释剂治疗慢性精神分裂症阴性症状的疗效和不良反应。方法:将78例慢性精神分裂症患者随机分为合用组(阿立哌唑合并文拉法辛缓释剂)和单用组(阿立哌唑),采用阳性症状和阴性症状量表(PANSS)、阴性症状量表(SANS)和治疗中出现的症状量表(TESS)于治疗前、治疗4、8、12周进行疗效及不良反应评定。结果:治疗8周合用组PANSS总分、阴性因子分,SANS总分及分量表分均比治疗前明显下降,且阴性因子分显著低于单用组。治疗后4、8、12周TESS评分,合用组低于单用组。结论:阿立哌唑合并文拉法辛缓释剂能明显改善慢性精神分裂症的阴性症状,且不良反应较少。
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| 关 键 词： | 慢性精神分裂症 阴性症状 阿立哌唑 文拉法辛缓释剂 |
Auxiliary therapy effect of veniafaxine in the trentment of chronic schizophrenia |
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| LIU Hao,ZHU Huai-xuan,ZHAO Qin,TAN Quan.Auxiliary therapy effect of veniafaxine in the trentment of chronic schizophrenia[J].Journal of Clinical Psychological Medicine,2009,19(4). |
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| Authors: | LIU Hao ZHU Huai-xuan ZHAO Qin TAN Quan |
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| Institution: | LIU Hao,ZHU Huai-xuan,ZHAO Qin,TAN Quan.Chongqing Mental Hospital,Chongqing 400038,China |
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| Abstract: | Objective:To evaluate the effect of aripiprazole plus extended-release venlafaxine on the negative symptoms of chronic schizophrenia.Method:78 chronic schizophrenia patients with mainly negative symptoms were randomly divided into study group and control group and observed for 12 weeks.The study group received aripiprazole plus extended-release venlafaxine,and the control group was only treated with aripiprazole.The clinical effect and side effects were assessed with PANSS,SANS and TESS before and after the... |
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| Keywords: | chronic schizophrenia negative symptoms aripiprazole extended-release venlafaxine |
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