Endoscopic ultrasound-guided fine-needle aspiration for the diagnosis of pancreatic cysts by combined cytopathology and cystic content analysis |
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Authors: | Amanda K Martin Zhongren Zhou |
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Institution: | Amanda K Martin, Zhongren Zhou, Department of Pathology and Laboratory Medicine, University Rochester, Rochester, NY 14642, United States |
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Abstract: | Recent advances in imaging technology have resulted in an increase in incidental discoveries of pancreatic cystic lesions. Pancreatic cysts comprise a wide variety of lesions and include non-neoplastic cysts and neoplastic cysts. Because some pancreatic cysts have more of a malignant potential than others, it is absolutely essential that an accurate diagnosis is rendered so that effective care can be given to each patient. In many centers, endoscopic ultrasound (EUS)-guided fine-needle aspiration (FNA) has emerged as the modality of choice that enables one to distinguish between mucinous and non-mucinous lesion, diagnose malignancy and collect cyst fluid for further diagnostic studies, such as pancreatic enzyme levels, molecular analysis and other tumor biomarkers. The current review will focus on EUS-guided FNA and the cytological diagnosis for pancreatic cysts. |
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Keywords: | Pancreatic cyst Endoscopic ultrasound Fine needle aspiration Diagnosis Cystic fluid analysis Cytology |
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