| IRF-4结合蛋白对人涎腺腺样囊性癌细胞增殖的抑制作用 |
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| 引用本文： | 熊剑,简从相,李鹏,范舒,申涛,常慧君,胡川闽,周继祥.IRF-4结合蛋白对人涎腺腺样囊性癌细胞增殖的抑制作用[J].第三军医大学学报,2011,33(6):554-557. |
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| 作者姓名： | 熊剑 简从相 李鹏 范舒 申涛 常慧君 胡川闽 周继祥 |
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| 作者单位： | 熊剑,Xiong Jian(400038,重庆,第三军医大学西南医院口腔科;437100,湖北,咸宁,咸宁学院口腔系);简从相,申涛,常慧君,周继祥,Jian Congxiang,Shen Tao,Chang Huijun,Zhou Jixiang(第三军医大学西南医院口腔科,重庆,400038);李鹏,范舒,胡川闽,Li Peng,Fan Shu,Hu Chuanmin(第三军医大学临床生物化学教研室,重庆,400038) |
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| 基金项目： | 国家自然科学基金，重庆市自然科学基金 |
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| 摘 要： | 目的 探讨IRF-4结合蛋白(IRF-4 binding protein,IBP)对人涎腺腺样囊性癌细胞增殖的影响.方法 用免疫组化(S-P法)染色技术对27例人涎腺腺样囊性癌组织和20例正常涎腺组织标本进行IBP表达的检测和分析.用脂质体法转染IBP过表达及空白对照载体至人腺样囊性癌细胞株ACC2,G418筛选后建立...
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| 关 键 词： | 免疫组化 IRF-4结合蛋白 克隆形成 |
Inhibitory effect of IRF-4 binding protein on proliferation of human salivary adenoid cystic carcinoma cells |
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| Xiong Jian,Jian Congxiang,Li Peng,Fan Shu,Shen Tao,Chang Huijun,Hu Chuanmin,Zhou Jixiang.Inhibitory effect of IRF-4 binding protein on proliferation of human salivary adenoid cystic carcinoma cells[J].Acta Academiae Medicinae Militaris Tertiae,2011,33(6):554-557. |
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| Authors: | Xiong Jian Jian Congxiang Li Peng Fan Shu Shen Tao Chang Huijun Hu Chuanmin Zhou Jixiang |
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| Institution: | Xiong Jian1,3,Jian Congxiang1,Li Peng2,Fan Shu2,Shen Tao1,Chang Huijun1,Hu Chuanmin2,Zhou Jixiang1(1Department of Stomatology,Southwest Hospital,2Department of Clinical Biochemistry and Laboratory Sciences,Third Military Medical University,Chongqing,400038,3Department of Stomatology,Xianning University,Xianning,Hubei Province,437100,China) |
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| Abstract: | Objective To investigate the effect of IRF-4 binding protein(IBP) on human salivary adenoid cystic carcinoma(SACC) cell proliferation.Methods IBP expression was detected and analyzed in 27 paraffin-embedded human SACC tissue specimens and 20 paraffin-embedded normal salivary gland tissue specimens with immunohistochemical staining(S-P method).ACC2 human SACC cells was transfected with plasmid pEGFP-C1/IBP(IBP group) and blank control plasmid pEGFP-C1(control group) via lipofection.Then,the positive cells we... |
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| Keywords: | IRF-4 binding protein salivary adenoid cystic carcinoma inhibition |
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