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Simultaneous TLR2 inhibition and TLR9 activation synergistically suppress tumor metastasis in mice
Authors:Jun YAN  Fang HUA  Han-zhi LIU  Hong-zheng YANG  Zhuo-wei HU
Affiliation:Molecular Immunology and Pharmacology Laboratory State Key Laboratory of Bioactive Substance and Function of Natural Medicines; Institute of Meteria Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China
Abstract:
Keywords:B16-F10 cells  tumor microenvironment  metastasis  Toll-like receptor 2  Toll-like receptor 9  Toll-like-receptor 2-neutralizing antibody  CpG  immunotherapy
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