结直肠癌病人术前肠道准备方法的改进

目的 探讨结直肠癌病人术前肠道准备方法改进的可行性.方法 60例结直肠癌病人按分层随机方法分为实验组和对照组,每组30例.实验组术前1 d口服硫酸镁加糖盐水;对照组采用传统术前3 d肠道准备方法.两组病人在肠道准备前后均检测外周静脉血血红蛋白浓度、血细胞比容和血清部分离子水平,监测体重,分析肠道菌群,比较肠道准备过程中腹泻次数,观察肠道清洁程度,以及手术前后病人一般情况、手术并发症.结果 实验组在肠道准备耐受性、手术前的腹泻状况明显优于对照组（P＜0.05）;两组血液检验指标、肠道清洁度差异无统计学意义（P＞0.05）;对照组术后并发症发生率高于实验组,但差异无统计学意义（P＞0.05）;实验组术后肠道菌群无明显变化,对照组术后肠道菌群变化明显.结论 结直肠癌病人改进的肠道准备方法简单,缩短肠道准备时间,提高病人耐受性,避免术后菌群紊乱,可替代传统的3 d准备法.

Improving pre-operative bowel preparation in colorectal cancer patients

Objective To study the feasibility of improving pre-operative bowel preparation in colorectal cancer patients. Methods Sixty cases were randomly divided into two groups with thirty cases in each group. The experimental group was performed oral magnesium sulfate combination with glucose normal saline the day before surgery while the control group was conducted the ordinary pre-operative bowel preparation.All of the cases were tested for peripheral blood hemoglobin concentration, hematocrit and part of the serum ion levels before and after bowel preparation. Weight was measured and intestinal flora was analyzed before and after surgery preparation. The number of diarrhea was counted in the process of bowel preparation and intestinal cleanliness was observed during operation. Patients' general condition and complications were observed before and after surgery. Results Compared with the control group, the experimental group outperformed in terms of bowel preparation tolerance and the number of preoperative diarrhea(P＜0.05). Blood tests indicated that there was no significant difference in intestinal cleanliness between the two groups (P＞0.05). The incidence of postoperative complications in the control group was higher than that in the experimental group, which, however,was not significant (P＞0.05). In the experimental group, no significant change of intestinal flora was observed, whereas intestinal flora changed significantly in the control group. Conclusions The revised bowel preparation for colorectal cancer patients is simple. It can shorten the process of bowel preparation, increase patients' tolerance, and prevent postoperative flora disorder.