Prognosis in patients with left bundle branch block and normal dipyridamole thallium-201 scintigraphy |
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Authors: | Victor M Gil Manuel Almeida António Ventosa Jorge Ferreira Carlos Aguiar Roão Calqueiro Ricardo Seabra-Gomes |
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Institution: | 1. Centro Cardiologico Monzino, IRCCS, Milan, Italy;2. Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy;3. Division of University Cardiology, IRCCS Ospedale Galeazzi-Sant''Ambrogio, Milan, Italy;4. Sports Medicine Unit, Catholic University of the Sacred Heart, Rome, Italy |
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Abstract: | Background The presence of complete left bundle branch block (LBBB) is commonly associated with a poorer prognosis, especially in patients
with coronary artery disease (CAD). In the general population with suspected CAD and normal intraventricular conduction, a
normal dipyridamole-thallium scintigraphy is a strong marker of a favorable outcome.
Objective Our objective was to assess the prognosis in patients with LBBB and a normal dipyridamole thallium-201 scintigram.
Population and methods Patients with complete LBBB and normal myocardial perfusion on dipyridamole SPECT thallium-201 scintigraphy performed in our
center for suspected CAD between 1988 and 1995 were monitored for clinical events.
Results Sixty-nine patients (36 women and 33 men) with a mean age of 59 years (range 56 to 61) were monitored for a mean period of
33 months (range 25 to 35). During this period, 4 patients had unstable angina, 2 of whom underwent myocardial revascularization.
There were no deaths or myocardial infarction. All events occurred at least 2 years after the thallium-201 scintigraphy.
Conclusion The presence of a normal myocardial perfusion with dipyridamole thallium-201 scintigraphy in this group of patients with suspected
CAD and LBBB was associated with a very good prognosis, a low rate of clinical events occurring only 2 years after the myocardial
scintigraphy, and no hard events. |
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Keywords: | left bundle branch block thallium-201 dipyridamole scintigraphy |
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