西藏那曲地区就诊患者人群ABO血型分布

目的 了解西藏北部高原那曲地区就诊患者血型分布情况.方法 收集2017年1月～2019年12月在那曲市人民医院就诊的做过ABO血型鉴定的全部5 258名患者的相关数据,做统计学分析与Hardy-Weinberg吻合度检测,并重点分析贫血、高原红细胞增多症、妇产科及罹患不同系统疾病患者的血型分布特点.结果 本组就诊患者的...

ABO blood group profile of patients in Naqu,Tibet:An analysis from a district-central hospital

Objective To investigate the distribution of ABO blood type of patients in Naqu, northern Tibet Plateau. Methods Blood group data of 5258 patients who underwent blood group identification in People′s Hospital of Naqu from 2017 to 2019 were retrospectively collected. Statistical analysis and Hardy-Weinberg coincidence test were conducted, and the disease profile, including anemia, high altitude polycythemia, obstetrics & gynecology, etc., of patients with different blood types was analyzed. Results Analysis showed that type O was most prevalent with the proportion of 37.73%(1 983/5 258), following with type B 34.12%(1 794/5 258), type A 21.3%(1 120/5 258)and type AB 6.85%(360/5 258).The distribution of ABO blood group was in accordance with Hardy-Weinberg equilibrium law, showing a trend of O>B>A>AB, and the trend of gene frequency was r>q>p. The distribution of ABO blood group in male and female patients was basically the same, and showed the trend of O>B>A>AB. The distribution of ABO blood group in Naqu area was similar to other high altitude areas of Tibet(P>0.05), but presented a certain difference with that in low altitude areas of Tibet(P<0.05). The distribution characteristics of ABO blood group in anemia, high altitude polycythemia and obstetrics & gynecology patients were also in accordance with Hardy-Weinberg equilibrium, showing a trend of O>B>A>AB. Blood group distribution of patients with different systemic diseases was different, but with no statistical significance. Conclusion The profile of ABO blood group of patients in Naqu area is consistent with that in high altitude areas of Tibet, but quite different from that in low altitude areas of Tibet. Knowing the distribution characteristics of ABO blood group of patients in this area(hospital) is helpful to formulate a set of safe and reasonable blood use(storage) plan and ensure clinical blood use, especially emergency blood use.