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Identification of the very uncommon allele HLA-Cw*0716 in a Caucasian renal transplant recipient: extension of the exon 4 sequence
Authors:Canossi A  Liberatore G  Del Beato T  Piazza A  Adorno D
Affiliation:CNR Institute 'Organ Transplants and Immunocitology', L'Aquila, Italy;
CNR Institute 'Organ Transplants and Immunocitology', Rome, Italy
Abstract:This report describes the unknown exon 4 sequence of the rare human leukocyte antigen-Cw*0716 allele, identified in a Caucasian renal transplant recipient from Italy. This sequence is identical to the Cw*070101 allele, and this result allowed us to confirm the hypothesis of the generation of Cw*0716 allele by an interallelic recombination event between Cw*0701/0706/0718 and Cw*020202 allele.
Keywords:Cw*0716    exon 4    HLA    new allele    sequence-based typing
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