Identification of the very uncommon allele HLA-Cw*0716 in a Caucasian renal transplant recipient: extension of the exon 4 sequence |
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Authors: | Canossi A Liberatore G Del Beato T Piazza A Adorno D |
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Affiliation: | CNR Institute 'Organ Transplants and Immunocitology', L'Aquila, Italy; CNR Institute 'Organ Transplants and Immunocitology', Rome, Italy |
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Abstract: | This report describes the unknown exon 4 sequence of the rare human leukocyte antigen-Cw*0716 allele, identified in a Caucasian renal transplant recipient from Italy. This sequence is identical to the Cw*070101 allele, and this result allowed us to confirm the hypothesis of the generation of Cw*0716 allele by an interallelic recombination event between Cw*0701/0706/0718 and Cw*020202 allele. |
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Keywords: | Cw*0716 exon 4 HLA new allele sequence-based typing |
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