| Generation of bcl-2 antisense RNA promotes apoptosis of human promyelocytic leukemia cell line HL-60 |
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| 作者姓名： | 朱峰 王成济 惠宏襄 赵永同 金明 |
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| 作者单位： | Department of Biochemistry，Fourth Mlitary Medical Univeresny，Xi'an，710032 |
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| 摘 要： | SupportedbytheNationaINaturalScienceFoundationofChina,No.3957o79ONotonlydoesapoptosisplayakeyroleinhomeostasis,butalsohascloserelationshipwithtumorigenesisandtumorregression,aswellaswiththechemotherapeuticandradiotherapeuticef-fectsontumorslJ.Justasthecellproliferation,thecellapoptosisisalsomodulatedbymanygenes,includingsomeoncogenesandtumorsup-pressorgenes(p53,bcl-2,c-my,etc.)2].Forex-ample,thehighexpressionofbcl-2inleukemiacellscanobviouslyinhibittheapoptosisinducedbytheremovalofgrowth…
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Generation of bcl-2 antisense RNA promotes apoptosis of human promyelocytic leukemia cell line HL-60 |
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| Zhu Feng,Wang Chengji,Hui Hongxiang,Zhao Yongtong,Jin Ming.Generation of bcl-2 antisense RNA promotes apoptosis of human promyelocytic leukemia cell line HL-60[J].Journal of Medical Colleges of PLA(China),1997(2). |
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| Authors: | Zhu Feng Wang Chengji Hui Hongxiang Zhao Yongtong Jin Ming |
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| Abstract: | |
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| Keywords: | bcl-21 antisense RNA HL-60 cells apoptosis |
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