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Frequency data on four tetrameric STR loci D18S1270, D14S608, D16S3253 and D21S1437 in a Korean population
Authors:Murim Choi  Jun Hwan Kim  Dong Hoon Lee  Seung Hwan Lee  H M Rho
Institution:(1) Department of Molecular Biology, and Research Center for Cell Differentiation, Seoul National University, Seoul 151-742, Korea Tel. +82-2-8806688, Fax +82-2-8887784, KR;(2) Laboratory of DNA Analysis, Supreme Public Prosecutor’s Office, Seoul 137-756, Korea, KR
Abstract:We present the results of a population study in Korea for four new tetrameric short tandem repeat (STR) loci employing multiplex PCR amplification, polyacrylamide gel electrophoresis of the PCR products and silver staining, which allow single base pair resolution and rapid typing. The loci tested were D18S1270, D14S608, D16S3253 and D21S1437 and all loci showed no significant deviations from Hardy-Weinberg equilibrium in more than 100 unrelated Koreans. This allelic frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a multiplex PCR based DNA profile in the Korean population. Received: 13 January 1999 / Received in revised form: 14 June 1999
Keywords:Quadruplex  Short tandem repeat  DNA typing  Korean population
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