骨巨细胞瘤的诊断与治疗

骨巨细胞瘤(GCT)是一种高侵袭性良性骨肿瘤,主要发生于年轻人中,骨端发病典型的影像学是骨端完全溶骨的膨胀性改变,多不伴有骨膜反应及软组织包块;CT、磁共振可以很好地显示肿瘤的侵及范围;X线平片最具诊断意义。圆形及卵圆形基质细胞及多核巨细胞是GCT的基本结构成分。刮除术是治疗GCT的基本外科手段,但其复发率较高。行刮除术的同时应用高速磨钻处理髓腔或用液氮冷冻、石碳酸烧灼、50%氯化锌液体浸泡以及放疗等辅助方法处理刮除后的病灶,可明显降低复发率。

Diagnosis and Treatment of Giant Cell Tumor of Bone

Giant cell tumor(GCT) of bone is a kind of highly invasive benign bone tumor.It mainly occurs in young adults.The typical pathogenetic image at bone end is the entire osteolytic expansibility changes,and is seldom accompanied by periosteal reaction and soft tissue masses.The invaded range of tumor can be well displayed by CT and magnetic resonance.X-ray has most diagnostic significance.The round and ovate stromal cells and multinucleated giant cells are the basic structural component of GCT of bone.Curettage is the basic surgical method to treat GCT of bone.But it has a higher recurrence rate.It can obviously reduce the recurrence rate by application of various auxiliary mechods such as dealing with pulp chamber by high speeding burr,or freezing with the liquid nitrogen,cauterization with phenol,fluid soaking with 50% zinc chloride for lesions after curettage.