腹腔镜与开腹肝叶(段)切除治疗肝癌的近期效果对比研究

目的探讨腹腔镜肝叶切除治疗肝癌的近期效果. 方法将2001年1月～2004年6月17例肝癌行腹腔镜肝叶(段)切除者与同期22例肝癌开腹肝切除者进行对比,比较两组手术时间、术中出血量、输血量、手术前后肝功能和血象、并发症等. 结果腹腔镜组手术时间长于开腹组(中位数300 min vs 145 min,u=107.05,P=0.023).两组术中出血量、输血量相近.腹腔镜组胆红素、丙氨酸转氨酶改变比开腹组小.两组手术前后血象改变无显著差异.腹腔镜组术后无并发症,开腹组有伤口感染、膈下积液、胸腔积液及术后出血各1例. 结论电视腹腔镜肝叶(段)切除治疗肝癌有明显微创效果,安全、有效.

A comparison study of laparoscopic versus open liver lobectomy (segmentectomy) for hepatocellular carcinoma

Objective To investigate short-term effects of laparoscopic liver lobectomy for the treatment of hepatocellular carcinoma. Methods A comparison was made between 17 cases of laparoscopic liver lobectomy (segmentectomy) (Laparoscopic Group) and 22 cases of open hepatectomy (Open Group) from January 2001 to June 2004. The operative time, blood loss, blood transfusion amount, liver functions and blood picture before and after the surgery, and complications between the two groups were compared respectively. Results The operative time was longer in the Laparoscopic Group (median, 300 min) than in the Open Group (median, 145 min) ( u =107.05, P =0.023). Both groups presented a similar appearance in the blood loss and the blood transfusion amount. Serum levels of bilirubin and ALT varied within narrower limits in the Laparoscopic Group than in the Open Group. No significant difference was seen in blood pictures before and after the surgery in both groups. No complications happened in the Laparoscopic Group, whereas 4 cases of complications were observed in the Open Group (1 case of incision infection, 1 case of hydrothorax, 1 case of subphrenic dropsy, and 1 case of postoperative bleeding). Conclusions Laparoscopic liver lobectomy (segmentectomy) for hepatocellular carcinoma is minimally invasive, safe and effective.