Value of positron emission tomography/computed tomography in diagnosis and staging of primary ocular and orbital tumors |
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Authors: | Ka-Hoi Hui Margaret L. Pfeiffer Bita Esmaeli |
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Affiliation: | 1. Section of Ophthalmology, Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA;2. The University of Texas Medical School at Houston, Houston, TX, USA |
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Abstract: | Accurate and reliable staging methods are crucial for optimal care of patients with ocular and orbital malignancies. Positron emission tomography/computed tomography (PET/CT) has recently emerged as a staging tool in the field of ophthalmic oncology. For detecting primary ocular or orbital lesions, PET/CT does not seem to provide an advantage over clinical ophthalmologic examination or conventional imaging studies such as CT or magnetic resonance imaging of the orbit. However, PET/CT may detect distant metastatic lesions that conventional imaging studies miss. For orbital and ocular adnexal lymphoma, use of PET/CT has been proven to be feasible and is now accepted both as a standard part of the initial staging work-up and for the assessment of response to therapy. For other ophthalmic tumors, PET/CT seems most appropriate for advanced metastatic tumors of the orbit, eyelid, and eye, for which the detection of distant metastasis with 1 comprehensive study may be preferable to performing multiple CT scans with contrast. |
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Keywords: | Positron emission tomography/computed tomography Cancer staging Uveal melanoma Orbital tumors Orbital lymphoma MALT lymphoma |
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