2型糖尿病患者的抑郁症状与人格特质和运动行为的关系

目的:分析2型糖尿病患者的抑郁症状及其与人格特质、运动行为的关系。方法:选取2型糖尿病患者718人,基于病人健康问卷抑郁自评量表(PHQ-8)、大五人格量表简式版(CBF-PI-B)建立logistic模型,分析抑郁症状与人格特质的关系及运动行为的调节作用。结果:存在抑郁症状的患者161人(22.4%)。神经质与宜人性得分与抑郁症状正向关联(OR=1.08、1.08)。已经开始锻炼、男性、诊断时间较长的患者抑郁症状比例较低(OR=0.44、0.47、0.62),已使用药物/胰岛素的患者抑郁症状比例较高(OR=2.23);参与锻炼会降低神经质与抑郁症状之间的关系(OR=0.95),但对宜人性与抑郁之间的关系无影响(P>0.05)。结论:糖尿病患者的神经质、宜人性与抑郁症状关系密切;参与运动可以有效减弱神经质对抑郁的影响。

Relation of depressive symptoms to personality traits and exercise behavior in patients with type 2 diabetes

Objective:To analyze the relation of depressive symptoms to personality traits and exercise behavior in patients with type 2 diabetes.Methods:Totally 718 patients with type 2 diabetes were included in this study.They were assessed with the Patient Health Questionnaire-8(PHQ-8) and Chinese Big Five Personality Inventory Brief version(CBF-PI-B).Logistic model was established to analyze the associations between depressive symptoms and different personality traits among patients with type 2 diabetes, and further estimated the moderating effect of exercise behavior.Results:Totally 161 patients had depressive symptoms(22.4%).Neuroticism and agreeableness(OR=1.08,1.08) were associated with having depressive symptoms.People who had exercise, being male, with longer duration of diagnosis were more likely to have no depressive symptoms(OR=0.44,0.47,0.62),whereas people who had taken medication/insulin were more likely to have depressive symptoms(OR=2.23).Exercise could reduce the association between neuroticism and depression(OR=0.95),but had no effect on the relationship between agreeableness and depression(P>0.05).Conclusion:Neuroticism and agreeableness are associated with depression in patients with type 2 diabetes.Exercise has a significant moderating effect on the association between neuroticism trait and depression.