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小檗碱的药理研究及临床应用
引用本文:谢义明. 小檗碱的药理研究及临床应用[J]. 中国医院药学杂志, 1991, 11(12): 538-539
作者姓名:谢义明
作者单位:同济医科大学附属同济医院 武汉
摘    要:小檗碱通过竞争性阻断α-肾上腺能受体增强心房收缩力,起到抗心律失常和降血压的作用;通过促进胰岛β细胞修复和增生,使胰岛素释放增加,同时抑制糖元异生,和(或)促进糖酵解,产生降血糖的作用,通过抗胃肠道粘膜细菌感染治疗溃疡性胃肠道炎。因此,小檗碱临床应用前景广泛。

关 键 词:小檗碱  药理作用  临床应用

Stuay on the pharmacology and clinic an application of Berberine
Xie Yi-ming Tong-ji Affilicated Hospital of Tong-gi medical University Wuhan. Stuay on the pharmacology and clinic an application of Berberine[J]. Chinese Journal of Hospital Pharmacy, 1991, 11(12): 538-539
Authors:Xie Yi-ming Tong-ji Affilicated Hospital of Tong-gi medical University Wuhan
Affiliation:Xie Yi-ming Tong-ji Affilicated Hospital of Tong-gi medical University Wuhan 430030
Abstract:Berberine can increase atrium contratile forcet, through competitive blockingof adrenergic-receptors It has antiarrhy thmic and antihypotensive effect. It canimprove the insulin release by means of enforcine the restortion and reproduct-ion of insula cells and inhibit gluconeogenesis, or accelerate glucose fermentati-on, then, reduce blood sugar. It is also able to treat ulcerous gastroenteritis.
Keywords:Berbeine  Clinical application
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