| 疟原虫乳酸脱氢酶的研究和应用进展 |
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| 引用本文： | 江莉,ZHOU Shui-sen. 疟原虫乳酸脱氢酶的研究和应用进展[J]. 国际医学寄生虫病杂志, 2008, 35(4) |
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| 作者姓名： | 江莉 ZHOU Shui-sen |
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| 作者单位： | 1. 上海市疾病预防控制中心,上海,200336
2. National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention, Shanghai 200025, China |
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| 摘 要： | 疟原虫乳酸脱氢酶是疟原虫糖分解途径的关键酶,由无性期和有性期虫体产生.感染人类的4种疟原虫有不同的乳酸脱氢酶异构体,使其具有种属特异性,已成为新一代疟疾快速诊断方法的靶抗原.该文对近年来国内外有关疟原虫乳酸脱氢酶的研究与应用进展进行综述.
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| 关 键 词： | 疟原虫 乳酸脱氢酶 研究进展 |
Progress on research and application of Plasmodium lactate dehydrogenase |
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| JIANG Li,ZHOU Shui-sen. Progress on research and application of Plasmodium lactate dehydrogenase[J]. International JOurnal of Medical Parasitic Diseases, 2008, 35(4) |
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| Authors: | JIANG Li ZHOU Shui-sen |
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| Abstract: | Plasmodium lactate dehydrogenase (pLDH) is a key enzyme in the pathway of glycolysis of the parasite. It is produced by the malaria parasite at both sexual and asexual stages. There are different lactate dehydrogenase isomers in the 4 different Plasmodium species which infect human. The different features among the species have made the pLDH a new target antigen in the rapid diagnostic tests of malaria. This paper reviewed the recent progress on the research and application of pLDH. |
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| Keywords: | Plasmodium Lactate dehydrogenase Research progress |
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