糖尿病酮症酸中毒时胰岛素拮抗激素的变化

［ 目的］ 探讨胰岛素拮抗激素与糖尿病酮症酸中毒的关系．［ 方法］ 观察８ 例糖尿病酮症酸中毒患者在酮症酸中毒治疗前后血糖、血浆胰高血糖素、生长激素、血清皮质醇、三碘甲腺原氨酸、甲状腺素等，并进行对比．［ 结果］ 在糖尿病酮症酸中毒治疗前血中胰高血糖素、生长激素、皮质醇的浓度显著高于治疗后的水平．三碘甲腺原氨酸在糖尿病酮症酸中毒治疗后显著上升，与治疗前比较有显著性差异．甲状腺素在糖尿病酮症酸中毒治疗前后无差异．［ 结论］ 胰高血糖素、生长激素、皮质醇与糖尿病酮症酸中毒发病机理有关．糖尿病酮症酸中毒患者出现低三碘甲腺原氨酸综合症，提示有甲状腺功能损害

Changes of insulin antagonistic hormone in diabetic ketoacidosis

OBJECTIVE To study the relation between insulin antagonistic hormone and diabetic ketoacidosis.METHOD To determine the blood glucose,plasma pancreatic glucagon,growth hormone,serum cortisol,T 3,T 4 in the 8 cases of diabetic ketoacidosis and to compare the hormene differences between before and after treatment. RESULT The mean values of plasma pancreatic glucagon,growth hormone,serum cortisol in the groups of diabetic ketoacidosis are significantly higher than those in the control group. The mean value of T 3 significantly rises after treatment. No difference is found on the mean values of T 4 between before and after treatment.CONCLUSION The insulin antagonistic hormone is related to the diabetic ketoacidosis. The diabetic ketoacidosis patients show low T 3 syndrome indicating that the function of thyroid is harmed.