| 着床窗期宫腔镜下子宫内膜形态与性激素及其受体表达的研究 |
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| 引用本文： | 冯苗,李素春,潘萍,刘标英. 着床窗期宫腔镜下子宫内膜形态与性激素及其受体表达的研究[J]. 实用妇产科杂志, 2009, 25(5) |
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| 作者姓名： | 冯苗 李素春 潘萍 刘标英 |
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| 作者单位： | 广东省计划生育专科医院腔镜诊疗中心,广东,广州,510600 |
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| 基金项目： | 广东省科技厅攻关项目立项基金，广东省计划生育委员会科研立项基金 |
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| 摘 要： | 目的:探讨着床窗期宫腔镜下子宫内膜形态与性激素及其受体表达的关系.方法:对55例不孕患者及16例正常生育者在排卵后7～9天,行宫腔镜子宫内膜形态的检查,并检测血雌二醇、孕酮及内膜雌激素受体(ER)、孕激素受体(PR).结果:不孕组宫腔镜下子宫内膜血管及腺体发育较对照组差,差异有统计学意义(P＜0.05).内膜差组腺上皮细胞ER表达较内膜佳组弱,差异有统计学意义(P＜0.05);内膜差组间质PR表达较内膜佳组弱,差异有统计学意义(P＜0.05).结论:不孕患者子宫内膜ER、PR的低表达,可能是导致子宫内膜腺体和血管网发育不良的重要原因之一.通过宫腔镜观察子宫内膜腺体和血管形态是一种较好的、简单可行的评估子宫内膜容受性的方法.
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| 关 键 词： | 着床窗 子宫内膜 不孕 雌激素受体 孕激素受体 |
Study on the Hysteroscopic Endometrial Appearances and the Expression of Sex-Hormone Receptor at the Implantation Window |
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| FENG Miao,LI Suchun,PAN Ping,et al. Study on the Hysteroscopic Endometrial Appearances and the Expression of Sex-Hormone Receptor at the Implantation Window[J]. Journal of Practical Obstetrics and Gynecology, 2009, 25(5) |
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| Authors: | FENG Miao LI Suchun PAN Ping et al |
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| Affiliation: | Guangdong Provincial Family Planning Research Institute;Guangzhou Guangdong 510600;China |
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| Abstract: | Objective:To explore the relation between the hysteroscopic endometrial appearance and the expression of sex-hormone receptor at the implantation window.Methods:55 infertile women and 16 fertile women underwent hysteroscopy at the implantation window,and meanwhile the levels of estradiol(E2)/progesterone(P)in the serum and the expression of estrogen receptor(ER) /progesterone receptors(PR) in the endometrium were examined.Results:There was significant difference between the infertile women with the fertile ... |
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| Keywords: | Implantation window Endometrium Infertility Estrogen receptor Progesterone receptors |
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