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感染性疾病患儿SIL-2R和T淋巴细胞亚群的测定
引用本文:营丽娟,何浩明,刘建胜,田小平. 感染性疾病患儿SIL-2R和T淋巴细胞亚群的测定[J]. 淮海医药, 2001, 19(6): 447-448
作者姓名:营丽娟  何浩明  刘建胜  田小平
作者单位:江苏省连云港市第一人民医院检验科
摘    要:目的:探讨了婴幼儿感染性疾病患儿血清SIL-2R和T淋巴细胞亚群的水平。方法:采用双抗体夹心法测定SIL-2R水平和间接免疫荧法测定了T淋巴细胞亚群。结果:患组血清SIL-2R水平显高于对照组(P<0.01),CD3,CD4和CD4/CD8比值均降低(P<0.01),CD8水平升高,结论:感染性疾病患儿存在有细胞免疫功能的降低及免疫调节的紊乱。

关 键 词:传染病 白细胞介素2受体 T淋巴细胞亚群 实验室检测
文章编号:1008-7044(2001)06-0447-02
修稿时间:2001-04-11

Detection of soluble interleukin-2 receptor and T lymphocytes subsets in baby and children with infectious diseases
YING Lijuan,HE Haoming,LIU Jiansheng,et al.. Detection of soluble interleukin-2 receptor and T lymphocytes subsets in baby and children with infectious diseases[J]. Journal of Huaihai Medicine, 2001, 19(6): 447-448
Authors:YING Lijuan  HE Haoming  LIU Jiansheng  et al.
Affiliation:YING Lijuan,HE Haoming,LIU Jiansheng,et al.Lianyungang First People's Hospital,Jiangsu 222002,China
Abstract:Objective To explore the serum levels of soluble interleukin 2 receptor(SIL 2R) and T lymphocyte subsets in baby and children with infectious diseases.Methods SIL 2R was dectected with double antobody sandwich ELISA and T lymphocyte subsets with indirect imnunofluorescent technique.Results The patients' SIL 2R level was higher than that in normal controls( P <0.01),CD 8 lymphocyte were increased,while CD 3?CD 4 and the ratio of CD 4 to CD 8 were decreased.Conclusion The cellular imnune function is reduced and the imnune regulation is confused in baby and children with infectious disease.
Keywords:Communicable diseases/infancy childhood  Receptors  interleukin-2  T lymphocyte subsets
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