Abstract: | Sixteen patients with tardive dyskinesia were treated with vitamin E in an open trial of on–off–on design. Abnormal involuntary movement scale (AIMS) ratings were performed in every phase of the study. The patients exhibited a significant reduction in their mean AIMS score during vitamin E treatment. Thus, this finding may suggest a possible role for vitamin E in the treatment of tardive dyskinesia. © 1997 John Wiley & Sons, Ltd. |