肥厚型心肌病心功能异常的磁共振电影成像分析

目的 应用磁共振电影成像（ｃｉｎｅ－ＭＲＩ）方法探讨肥厚型心肌病的左心室功能的变化。方法 １２例肥厚型心肌病患者，行ＭＲ快速自旋回波（ＴＳＥ）多层面平扫和ｃｉｎｅ－ＭＲＩ检查，用ＡＲＧＵＳ专用心功能分析软件分析射血分数、心肌增厚率、心腔（左心室）容积及时间－容积变化曲线等参数。结果 （１）肥厚型心肌病主要累及左心室前、侧壁及室间隔，肥厚心肌的心肌增厚率显著低于正常心肌（ｔ＝１５．１，Ｐ〈０．０１）

Evaluation of malfunction of left ventricle in hypertrophic myocardiopathy with cine-MR imaging

Objective To study the morphology and left ventricular function in patients with hypertrophic cardiomyopathy with cine MRI Methods Twelve patients with hypertrophic cardiomyopathy were studied with TSE T 1WI and cine MRI, and some indices for the evaluation of cardiac function were measured using ARGUS auto quantitation program Results (1)The anterior and lateral wall of left ventricle and interventricular septum were often thickened in hypertrophic cardiomyopathy The thickening rate of hypertrophic myocardium was less than that of normal significantly ( t =15 1, P <0 01) at end systole (2)Left ventricular volume was decreased ( t =25 4, P <0 01) with low end diastolic function in asymmetric hypertrophic cardiomyopathy (3)The left ventricular outflow tract was narrow with longer ejection time Conclusion The myocardial thickening with decreased left ventricular function is often observed in hypertrophic cardiomyopathy Cardiac magnetic resonance imaging can provide useful morphologic and functional information