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Preoperative Systemic Bone Quality Does Not Affect Tibial Component Migration in Knee Arthroplasty: A 2-Year Radiostereometric Analysis of a Hundred Consecutive Patients
Authors:Karina N Linde  Frank Madsen  Katriina B Puhakka  Bente L Langdahl  Kjeld Søballe  Inger Krog-Mikkelsen  Maiken Stilling
Institution:1. Orthopedic Research Unit, Aarhus University Hospital, Aarhus, Denmark;2. Department of Clinical Medicine, Aarhus University, Aarhus, Denmark;3. Department of Orthopaedic Surgery, Aarhus University Hospital, Aarhus, Denmark;4. Department of Radiology, Aarhus University Hospital, Aarhus, Denmark;5. Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark
Abstract:BackgroundBone quality and other preoperative predictive factors may affect implant migration and the survival of knee arthroplasty.MethodsIn a prospective cohort of 100 consecutive patients (65 women) at a mean age of 67.7 years (range 39-87 years), we investigated preoperative predictors of postoperative tibial component migration in cemented and cementless total knee arthroplasties or cemented unicompartmental knee arthroplasty. Predictors consisted of Knee Injury and Osteoarthritis Outcome Score (KOOS) and Oxford Knee Score, questionnaires, bone turnover markers of CTX and P1NP, systemic bone mineral density (BMD), and knee osteoarthritis (OA) grade. Tibial component migration was measured with radiostereometry postoperative, at 1 and 2 years of follow-up.ResultsBetween 1 and 2 years, 19 tibial components migrated continuously (maximum total point motion MTPM] > 0.2 mm). In general, there was no difference in age, body mass index, BMD, KOOSs, or OA grade between patients with continuous tibial migration compared to patients without continuous migration (P > .11). However, cementless tibial components with continuous migration had a lower KOOS pain score (more pain), lower vitamin D, and a higher bone turnover (CTX) value than patients without continuous migration. There was no association between the BMD and MTPM at 1-year follow-up regardless of prothesis type (P > .17). Patients with osteoporosis and normal BMD had similar mean tibial component MTPM at 2 years (3 prostheses combined; P = .34).ConclusionMigration of tibial components inserted with or without bone cement was not affected by the preoperative bone quality in terms of systemic BMD, bone turnover markers, and OA grade in the knee.
Keywords:Reprint requests: Karina N  Linde  Orthopedic Research Unit  Aarhus University Hospital  Palle Juul-Jensens Blvd  99  Aarhus 8200  Denmark    RSA  bone mineral density  migration  knee arthroplasty  bone turnover markers
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