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Clinical Outcomes in Neurogenic Claudication Using a Multimodal Program for Lumbar Spinal Stenosis: A Study of 49 Patients With Prospective Long-term Follow-up
Authors:Ngai W Chow  Danielle Southerst  Jessica J Wong  Deborah Kopansky-Giles  Carlo Ammendolia
Institution:1. Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada;2. Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada;3. Graduate Education and Research Programs, Canadian Memorial Chiropractic College (CMCC), Toronto, Ontario, Canada;4. Occupational and Industrial Orthopaedic Centre, Langone Orthopaedic Hospital, New York University Langone Health, New York, NY;5. University of Ontario Institute of Technology-CMCC Centre for the Study of Disability Prevention and Rehabilitation, Toronto, Ontario, Canada;6. Department of Family and Community Medicine, St. Michael’s Hospital, Toronto, Ontario, Canada;7. Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada;8. Rebecca MacDonald Centre for Arthritis & Autoimmune Diseases, Mount Sinai Hospital, Toronto, Ontario, Canada;9. Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada;10. Department of Surgery, University of Toronto, Toronto, Ontario, Canada
Abstract:ObjectiveThe purpose of this study was to assess long-term outcomes of a 6-week multimodal program (manual therapy, exercises, and self-management strategies) in patients with neurogenic claudication due to degenerative lumbar spinal stenosis.MethodsThis study evaluated 49 patients with neurogenic claudication who completed a 6-week multimodal program between 2010 and 2013. Outcomes included Oswestry Disability Index (ODI), Zurich Claudication Questionnaire (ZCQ), and Numeric Rating Scale. Mean differences, paired t tests, and the Wilcoxon rank-sum test were used to compare outcomes at baseline, 6 weeks, and long-term follow-up.ResultsTwenty-three patients completed the follow-up questionnaire (47% response rate). Median follow-up was 3.6 years (interquartile range: 3.3-4.6). The mean age was 73.5 years (standard deviation: 8.5). Between baseline and long-term follow-up, there were statistically significant and clinically important improvements in disability (ODI: -23.7 95% confidence interval (CI): -15.7 to -31.6]; ODI walking item: -1.96 95% CI: -1.34 to -2.57]; ZCQ function scale: -0.42 95% CI: -0.10 to -0.70]) and pain (leg pain: -3.53 95% CI: -1.80 to -5.20]; ZCQ symptom scale: -0.71 95% CI: -0.30 to -1.10]), but not low back pain (Numeric Rating Scale: -1.03 95% CI: -1.00 to 3.10]). There was no statistically significant change in any outcomes between 6 weeks and long-term follow-up.ConclusionIn a sample of patients with neurogenic claudication participating in a 6-week multimodal program, clinically important improvements in leg pain and disability, but not low back pain while walking, were maintained in the long term (median duration of 3.6 years) when compared to baseline.
Keywords:Corresponding author: Ngai W  Chow  DC  6100 Leslie Street  Toronto  Ontario  M2H 3J1  Canada  Tel  : +1 416 482 2546    Spinal Stenosis  Lumbar Vertebrae  Osteoarthritis  Spine  Rehabilitation  Chiropractic  Intermittent Claudication  Musculoskeletal Manipulations
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