Pyrophosphate-induced inflammation: An in vivo study of the interrelationship of intracellular cyclic AMP and cyclic GMP |
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Authors: | D. A. Deporter P. Dieppe D. A. Willoughby |
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Affiliation: | (1) Department of Rheumatology and Experimental Pathology, St. Bartholomew's Hospital, London;(2) Department of Pharmacology, Hôpital Cochin, Paris |
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Abstract: | The changes in leucocyte concentrations of cyclic AMP and cyclic GMP were monitored during pyrophosphate-induced pleurisy in rats. A classical Yin Yang relationship was demonstrated. |
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