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全自动生化分析仪检测G6PD活性在孕检中的意义
引用本文:黄倩婷,贾璋林,吕伟标.全自动生化分析仪检测G6PD活性在孕检中的意义[J].四川生殖卫生学院学报,2009(6):43-44.
作者姓名:黄倩婷  贾璋林  吕伟标
作者单位:[1]广州中医药大学附属南海妇幼保健院检验科,广东南海528200 [2]南方医科大学附属顺德第一人民医院检验科,广东顺德528300
摘    要:目的:探讨全自动生化分析仪检测G6PD活性对孕妇产前体检时G6PD缺乏和地中海贫血初筛的意义。方法:200份标本用生化分析仪检测G6PD活性,同时作高铁血红蛋白还原(MHB—RT)检测和血红蛋白电泳检测。结果:用生化仪检测G6PD活性其降低者与高铁血红蛋白还原检测结果极为吻合(吻合系数κ=0.872);G6PD活性增高者与血红蛋白电泳时发现地中海贫血的结果也极为吻合(吻合系数,κ=0.862)。结论:用全自动生化分析仪直接快速检测G6PD活性,对孕妇产前G6PD缺乏和地中海贫血的初筛具有重要意义。

关 键 词:G6PD活性  G6PD缺乏  地中海贫血

On G6PD Activity Test by ACA in Pregnancy Examinations
HUANG Qian-ting,JIA Zhang-lin,LV Wei-biao.On G6PD Activity Test by ACA in Pregnancy Examinations[J].Journal of Sichuan Reproductive Health Institute,2009(6):43-44.
Authors:HUANG Qian-ting  JIA Zhang-lin  LV Wei-biao
Institution:(Guangzhou University of Chinese Medicine, Nanhai, Guangdong, 528200; Southern Medical University, Shunde, Guangdong, 528300)
Abstract:Objective: To explore the significance of test of G6PD activity by ACA to G6PD deficiency and Mediterranean anemia detect in pregnancy examinations. Methods: 200 samples accepted G6PD activity test by ACA, at the same time, MHB-RT and HEE tests were made. Results: The test results of samples that G6PD activity reduced tallied with that of MHB-RT test. The test results of samples that G6PD activity increased tallied with that of HEE test. Conclusion: The test of G6PD activity by ACA has important significance to G6PD deficiency and Mediterranean anemia detect in pregnancy examinations.
Keywords:G6PD activity  G6PD deficiency  Mediterranean anemia
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