Why clinical trials of AIDS vaccines are premature. |
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Authors: | W K Mariner |
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Institution: | Boston University, School of Public Health and School of Medicine, MA 02118. |
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Abstract: | Considering the current state of scientific knowledge and the fact that no relevant animal model exists for demonstrating a vaccine's probable efficacy, the fundamental prerequisites for testing experimental AIDS vaccines in human beings have not been met. The ethical obligations of informed consent, patient confidentiality, and the balancing of risks and benefits are examined in a call for more public debate on the issue before clinical trials are begun. |
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