| 完全轮廓法的研究进展及在肺内液表面特性测量中的应用 |
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| 引用本文： | 沙敬新,陈正龙,张春元,刘远洋,黄湘岳,胡兆燕.完全轮廓法的研究进展及在肺内液表面特性测量中的应用[J].生物医学工程学进展,2021(1):14-19. |
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| 作者姓名： | 沙敬新 陈正龙 张春元 刘远洋 黄湘岳 胡兆燕 |
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| 作者单位： | 上海理工大学医疗器械与食品学院;上海健康医学院医疗器械学院;国家药品监督管理局呼吸麻醉重点实验室 |
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| 摘 要： | 完全轮廓法(ADSA)是一种通过分析液滴/气泡轮廓以计算表面张力和接触角的方法,其结合各种滴形控制装置可以满足不同的应用需求.首先简单介绍了完全轮廓法的测量原理以及悬滴法、捕获气泡法和限制性座滴法等几种典型的滴形控制装置,然后综述了最新的ADSA表面张力计算方法以及它们各自的优缺点.ADSA法相对于膜天平等传统的表面张...
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| 关 键 词： | 表面张力 轴对称液滴形状分析 滴形装置 算法 肺内液 |
Research Progress of Complete Profile and its Application in Measurement of Surface Characteristics of Pulmonary Fluid |
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| Authors: | SHA Jingxin CHEN Zhenglong ZHANG Chunyuan LIU Yuanyang HUANG Xiangyue HU Zhaoyan |
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| Institution: | (School of Medical Instrument and Food Engineering,University of Shanghai for Science and Technology,Shanghai,200093;School of Medical Instrument,Shanghai University of Medicine and Health Science,Shanghai,201318;NMPA Key Laboratory for Respiratory and Anaesthetic Equipment,Shanghai,201318) |
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| Abstract: | Axisymmetric Drop Shape Analysis(ADSA)is a technique for measuring surface tension and contact angles according to the shape of drops/bubbles.It can meet different application requirements when it is combined with various drop shape control devices.We first briefly introduces the measurement principle of ADSA and some typical drop shape control devices,such as pendant drop method,captive bubble method,and constrained sessile drop method.Then,the latest calculation methods of surface tension according to ADSA,as well as their advantages and disadvantages,are summarized.Compared with the film balance method and other conventional techniques,ADSA method has numerous advantages,such as high measurement automation,small sample required,and dynamic measurement of surface tension.It is expected to be widely used in the surface tension measurement of pulmonary surfactants,the study of dynamic adsorption process,and the high-fidelity biophysical simulation of pulmonary surfactants in the future. |
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| Keywords: | surface tension ADSA droplet shape device algorithm pulmonary fluid |
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