消化科就诊的艾滋病患者血液学检验异常的分析

目的探讨艾滋病(AIDS)患者血液分析特点。方法收集本院消化科2005年3月至2009年3月住院的20例AIDS患者,与同期住院相匹配的35例非AIDS/HIV感染者的血液学检查资料进行统计学分析,比较两组患者血液学差异。结果本组AIDS患者血常规普遍存在淋巴细胞比率、血红蛋白、红细胞总数下降,差异有统计学意义(P0.05);血生化大部分存在乳酸脱氢酶(LDH)、C-反应蛋白(CRP)、红细胞沉降率(ESR)升高,差异有统计学意义(P0.05),清蛋白(Alb)、胆碱酯酶(CHE)及清蛋白/球蛋白比(A/G)下降,差异有统计学意义(P0.05),血清总胆红素(TB)、天门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)均值显著较对照组升高,但TB、AST、ALT异常比率与对照组间差异无统计学意义(P0.05),甲状腺功能异常以血清游离T3(FT3)下降最为常见,差异有统计学意义(P0.05)。结论 AIDS患者常以消化道症状为主而就诊,血液学分析检查常呈现贫血、肝脏功能和内分泌功能异常以及提示机会性感染的存在。

Analysis of the hematological features of blood from the HIV AIDS patients with the symptoms of digestive tract as their chief complaint

Objective To investigate the haematological features of the patients with HIV/AIDS.Methods The haematological datas of 20 patients with HIV/AIDS and 35 non-HIV/AIDS infection patients,who were hospitalized in the Department of Gastroenterology of our hospital from March 2005 to March 2009,were retrospectively collected and the hemotological difference between the two groups were analyzed.Results The general blood test showed that the number of lymphocyte,erythrocyte and contents of haematoglobin in the HIV/AIDS patients were usually decreased,with the difference being of statistical significance（P0.05）,and the blood biochemistry test showed that contents of lactic acid dehydrogenase,C-reactive protein in serum samples always increased and blood sedimentation were generally incresed,with the difference being of statistical significance（P0.05）.Although the means of contents of total bilirubin,glutamate-pyruvate transaminase and glutamic oxalacetic transaminase often increased,the rate of their abnormality displayed no evident defferences,compared with the control group.Meanwhile,contents of albumin,cholinesterase and ratio of albumin to globulin often decreased,with the difference being of statistical significance（P0.05）.In addition,the free triiodothyronine 3（FT3）decreased evidently in the patients with HIV/AIDS,with the difference being of statistical significance（P0.05）.Conclusion Symptoms of digestive tract are generally regarded as the chief complaint for the patients with HIV/AIDS.In most cases,the analysis of blood of AIDS patients presented with anemia and hepatic lesion and disfunction of thyroid gland.Moreover,they often give some important clues to the diagnosis of some opportunistic infections as well.