1985～2008年间我国正常男性精液质量变化分析

目的:研究1985～2008年间国内正常男性精液质量变化趋势。方法:检索历年发表的精子质量方面的文献,系统收集相关资料和数据,利用散点图和直线回归法,分析近24年正常男性精液精子密度、精液量及精子总数的变化。结果:1985～2008年间国内正常男性精液质量参数中精液量没有明显变化(P>0.05)。1985～1994年精子密度和精子总数不存在与时间相关的变化(P>0.05),但自1995年后的14年以来,精子密度和精子总数呈现显著下降趋势(P<0.05),精子密度从1995年81.5×106/ml下降到2008年66.7×106/ml,每年降低1.40%;精子总数从1995年257.2×106下降到2008年的185.9×106,每年下降2.15%。结论:1985～1995年间国内正常男性精液质量未见明显变化,而1995～2008年14年间精子密度和精子总数明显降低,很可能与进入重化工时代引起的日益加重的环境污染有关。

Changes of semen quality in Chinese fertile men from 1985 to 2008

Objective :To analyze the changes of semen quality in Chinese fertile men during the past 24 years. Methods :We reviewed the literature on the sperm quality of Chinese fertile males published from 1985 to 2008,collected relevant data,and analyzed the changes in semen volume,sperm density,and total sperm count by linear regression. Results :There were no significant changes either in semen volume during the period of 1985-2008 (P>0.05),or in sperm density and total sperm count from 1985 to 1994 (P>0.05). However,significant decreases were observed during the latter 14 years in sperm density (from 81.5 × 106/ml in 1995 to 66.7 × 106/ml in 2008,with a mean annual reduction of 1.40%) and total sperm count (from 257.2×106 in 1995 to 185.9 × 106 in 2008,with a mean annual reduction of 2.15%) (P<0.05). Conclusion :The semen quality of Chinese fertile men showed no significant changes from 1985 to 1995,but evidently declined from 1995 to 2008,which may be attributed to the aggravated environmental pollution induced by heavy chemical industry.