中西医综合治疗慢性阻塞性肺疾病稳定期临床观察

目的:探讨中西医综合治疗对慢性阻塞性肺疾病(COPD)稳定期患者的疗效. 方法:采用随机、对照、单盲的临床试验方案采用随机对照单盲临床研究方法,将在呼吸专科门诊入选的COPD稳定期患者63例随机分为治疗组(n=32)与对照组(n=31). 两组患者均按相关指南采用西医基础治疗,治疗组32例除基础治疗外还加服玉屏风颗粒、百令胶囊,健脾益肺冲剂. 疗程均为3 mo. 结果:治疗组在增加6 min步行距离与生活质量评分、减少急性加重次数上优于对照组(P<0.05),而肺功能改善与对照组比较差异无统计学意义(P>0.05). 结论:中西医综合治疗较单纯西医基础治疗可提高患者的生活质量、行走耐力,减少其急性加重次数,不良反应轻微,患者依从性好.

Clinical observation of tranquilization period of chronic obstructive pulmonary disease treated by integration of traditional Chinese medicine and Western medicine

AIM: To explore the treatment effect of the integration of traditional Chinese medicine and western medicine on chronic obstructive pulmonary disease (COPD) patients in the tranquilization period. METHODS: Randomized controlled trial was conducted. Sixty-three COPD cases in the tranquilization period from our respiratory clinic were divided into two groups and were given basic western medical treatment. One of the groups, the treatment group, was also given Yupingfeng Granule, Bailing Capsules and Jianpiyifei Powder for 3 months. RESULTS: The treatment group was better than the other group in the six-minute walk distance, the score of quality of life and the times of acute exacerbation (P<0.05). There was no significant difference in pulmonary function between the two groups (P>0.05). CONCLUSION: Integrated treatment of traditional Chinese medicine and Western medicine, with mild adverse reaction and good compliance, can improve the quality of life, enhance the walking endurance and lessen the times of acute exacerbation.