| 166株铜绿假单胞菌的耐药谱分析 |
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| 引用本文： | 陈如,刘守桂.166株铜绿假单胞菌的耐药谱分析[J].华中科技大学学报(医学版),2000,29(6):602-604. |
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| 作者姓名： | 陈如 刘守桂 |
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| 作者单位： | 同济医科大学附属同济医院检验科，武汉 430030 |
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| 基金项目： | 卫生部科学研究基金资助项目(No. 95-0411) |
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| 摘 要： | 对1997年1月至1998年1月从临床标本分离培养的166株铜绿假单胞菌，应用K-B法测定该分离菌株对18种抗生素的耐药性。选择出其中113株作对7种首选抗生素的多重耐药分析。结果表明铜绿假单胞菌对青霉素类抗生素、一代头孢菌素、二代头孢菌素高度耐药，对三代头孢菌素和喹诺酮类抗生素比较敏感，该菌多重耐药有上升趋势。结果提示临床合理使用抗生素可避免或减少耐药菌株的出现。
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| 关 键 词： | 铜绿假单胞菌 耐药，抗生素 |
| 修稿时间： | 1998年12月24 |
Antibiotic Resistant Patterns in 166 Clinical Isolates of Pseudomonas aeruginosa |
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| Chen Ru,Liu Shougui.Antibiotic Resistant Patterns in 166 Clinical Isolates of Pseudomonas aeruginosa[J].Journal of Huazhong University of Science and Technology(Health Sciences),2000,29(6):602-604. |
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| Authors: | Chen Ru Liu Shougui |
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| Institution: | Chen Ru,Liu Shougui Department of Clinical Laboratory,Tongji Hospital,Tongji Medical University,Wuhan 430030 |
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| Abstract: | K-B method was used to determine the resistance of 166 strains of Pseudomonas aeruginosa iso- lated and cultured from clinical samples to 18 kinds of antibiotics. Multidrug resistance of the 113 isolates out of the 166 strains to 7 major drugs were evaluated. The results showed Pseudomonas aeruginosa was high resis- tant to penicillin, first- and second- generation cephalosporins, relatively sensitive to third-cephalosporins and quinolones. The trend of multidrug resistance of Pseudomonas aeruginosa was increased. It was suggested that clinical rational use of antibiotics could reduce or prevent the occurrence of resistant isolates. |
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| Keywords: | pseudomonas aeruginosa resistance antibiotics |
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