| 二联体亲子鉴定中常染色体STR基因座检测 |
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| 引用本文： | 薛小琦,莫耀南. 二联体亲子鉴定中常染色体STR基因座检测[J]. 郑州大学学报(医学版), 2004, 39(6): 986-988 |
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| 作者姓名： | 薛小琦 莫耀南 |
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| 作者单位： | 河南科技大学法医学系,洛阳,471003;河南科技大学法医学系,洛阳,471003 |
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| 基金项目： | 河南省科技攻关计划项目资助课题 99110 0 2 17 |
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| 摘 要： | 目的：探讨常染色体STR基因座检测在二联体亲子鉴定中的应用价值。方法：应用PCR同步扩增24个常染色体STR基因座，PAGE电泳分型，完成二联体亲子鉴定66例。结果：认定亲生关系38例(57．58％)，排除亲生关系28例(42．42％)。结论：经24个常染色体STR基因座检测，能确切地认定或排除亲生关系，得出正确的鉴定结论。
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| 关 键 词： | STR分型 单亲鉴定 认定亲生关系 排除亲生关系 |
| 修稿时间： | 2004-04-13 |
Detecting short tandem repeats loci on eutochromosome on diad paternity testing |
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| XUE Xiaoqi,MO Yaonan. Detecting short tandem repeats loci on eutochromosome on diad paternity testing[J]. Journal of Zhengzhou University: Med Sci, 2004, 39(6): 986-988 |
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| Authors: | XUE Xiaoqi MO Yaonan |
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| Affiliation: | XUE Xiaoqi,MO Yaonan Department of Forensic Medicine,Henan University of Science and Technology,Luoyang 471003 |
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| Abstract: | Aim: To study the application of PCR-STR DNA typing in forensic diad paternity testing. Methods: Using site-specific primers for 24 euchromosome STR loci, the individual genome DNA of 66 cases of diad paternity testing were typed after synchronized PCR and PAGE followed by silver staining. Results: The paternity were confirmed in 38 cases (57.58%) and excluded in 28 cases (42.42%).Conclusion: The paternity in diad paternity testing cases can be successfully confirmed or excluded after DNA typing of 24 euchromosome STR loci simultaneously. |
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| Keywords: | PCR-STR typing diad paternity testing paternity confirming paternity excluding |
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