Adverse events and practice variability associated with paediatric endotracheal suction: An observational study |
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Institution: | 1. Faculty of Nursing, Universitas Indonesia, Depok, West Java, Indonesia;2. Faculty of Medicine and Health Sciences, University of Nottingham, United Kingdom |
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Abstract: | ObjectiveThe objective of this study was to determine the incidence of endotracheal tube (ETT) suction–related adverse events (AEs) and to examine associations between AEs and patient and suction characteristics. Secondary objectives were to describe ETT suction practices in an Australian paediatric intensive care unit (PICU).MethodsA prospective, observational study was undertaken in a mixed cardiac and general PICU. Children were eligible for inclusion if they were intubated and mechanically ventilated. Data on patient and suction variables (indication for ETT suction, number of suction episodes per mechanical ventilation episode, indication for normal saline instillation NSI] and NSI dose) including potential predictive variables (age, Paediatric Index of Mortality 3 PIM3], NSI, positive end-expiratory pressure, and hyperoxygenation) were collected. The main outcome variable was a composite measure of any AE.Main resultsA total of 955 suction episodes were recorded in 100 children. AEs occurred in 211 (22%) ETT suctions. Suction-related AEs were not associated with age, diagnostic category, or index of mortality score. Desaturation was the most common AE (180 suctions; 19%), with 69% of desaturation events requiring clinician intervention. Univariate logistic regression showed the odds of desaturation decreased as the internal diameter of the ETT increased (odds ratio OR]: 0.59; 95% confidence interval CI]: 0.37–0.95; p = 0.028). Multivariable modelling revealed NSI was significantly associated with an increased risk of desaturation (adjusted OR aOR]: 3.23; 95% CI: 1.99–5.40; p < 0.001) and the occurrence of an AE (aOR: 2.76; 95% CI: 1.74–4.37; p < 0.001). Presuction increases in fraction of inspired oxygen (FiO2) was significantly associated with an increased risk of experiencing an AE (aOR: 2.0; 95% CI: 1.27–3.15; p = 0.003).ConclusionsETT suction–related AEs are common and associated with NSI and the requirement for pre-suction increases in FiO2. Clinical trial data are needed to identify high-risk patient groups and to develop interventions which optimise practice and reduce the occurrence of ETT suction–related AEs. |
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Keywords: | Endotracheal suction Adverse events Clinical audit Paediatric Intensive care Normal saline |
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