真空小梁成形术治疗原发性开角型青光眼患者的临床观察

目的：观察真空小梁成形术（PN T ）对原发性开角型青光眼患者的降眼压效果，体会患者对此治疗的依从性改变。方法选取我院2012年11月至2014年5月就诊的原发性开角型青光眼患者30例（45眼），入选患者门诊均行眼科一般检查、超声生物显微镜（UBM ）、Humphrey视野、海德堡 HRT、24 h眼压曲线（非接触眼压计）以确诊。患者单眼或双眼进行PNT 1000型治疗仪（Ophthalmic International公司产）治疗。治疗后1天、1周、2周、1个月、2个月复测眼压。首次治疗后半月重复治疗一次，此后每2～3月根据患者依从性可重复治疗。单眼治疗者选治疗眼，双眼者随机选1眼。结果治疗后1天、1周、2周、1月、2月各时间点眼压较治疗前眼压差异有统计学意义（P＜0.01）。无1例出现严重并发症。治疗后一年内6例患者重复治疗3次，6例患者治疗2次，7例患者治疗1次，11例患者未重复治疗。结论真空小梁成形术（PN T ）可安全有效地降低原发性开角型青光眼患者眼压，可用于开角型青光眼降眼压治疗，但筛选病人条件苛刻，且病人依从性较差，对治疗易失去耐心，应用范围较窄。

Clinical observation of primary open-angle glaucoma treated with PNT

Objective To study the efficiency of pneumatic trabeculoplasty (PNT) in primary open-angle glaucoma ,and expe-rience patients compliance changes .Methods In this study we selected 30 patients(45 eyes) of primary open-angle glaucoma in our hospital from November 2012 to May 2014 .All subjects underwent ultrasonic biology microscope ,HRT-III(Heideberg Ret-ina Tomograph) ,Humphrey visual field examinations and 24-hour intraocular pressure (IOP) measurement using non-contact tonometer .One or two eyes of each one were treated with PNT Model 1000 (Ophthalmic International Inc .) .The ophthalmic slitlamp microscope examinations and IOP measurement were repeated at 1 day ,1 week ,2 weeks ,1 month and 2 months after PNT therapy .Results The IOP of 1 day ,1 week ,2 weeks ,1 month and 2 months after PNT therapy were less than that be-fore therapy(P<0.01) .In one year after therapy ,6 patients complete repeated treatment three times ,6 patients complete two times ,7 patients complete one times ,11 patients did not repeat treatment .Conclusion This small sample study of PNT showed a potentially good IOP lowing effect on the primary open-angle glaucoma and hypertensive patients .However ,patient compli-ance is poor ,they will loose the patience easily ,and the filtration of patients is so rigorous that the application of PNT will be limited .